1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).
2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.
3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.
Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:
: Both Tadalafil and N nitrate can lower blood pressure. While taking these medications, be sure you understand the risks and side effects and how to take it. Cialis should be used with caution in individuals with certain heart conditions.
: Both Cialis and alpha-blockers that relax blood vessels can increase the blood pressure-lowering effects of the medication. If needed, this may cause dizziness or fainting, or orthostatic hypotension.
Other antihypertensive drugs (e.g.
Erection problems (impotence) are very common, particularly in men over 40.
Most men occasionally fail to get or keep an erection. This is usually due to stress, tiredness, anxiety or drinking too much alcohol, and it’s nothing to worry about.
If it happens more often, it may be caused by physical or emotional problems.
Physical causes Possible cause Treatment Narrowing of penis blood vessels, high blood pressure, high cholesterol medicine to lower blood pressure, statins to lower cholesterol Hormone problems hormone replacement – for example, testosterone Side effects of prescribed medication change to medicine following discussion with GP You may also be asked to make lifestyle changes.
Do lose weight if you’re overweight stop smoking eat a healthy diet exercise daily try to reduce stress and anxiety
Don’t cycle for a while (if you cycle more than 3 hours a week) drink more than 14 units of alcohol a week
Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them. These effects are normally mild to moderate in nature.
If you experience any of the following side effects stop using the medicine and seek medical help immediately:
allergic reactions including rashes (frequency uncommon). chest pain – do not use nitrates but seek immediate medical assistance (frequency uncommon). priapism, a prolonged and possibly painful erection after taking CIALIS (frequency rare). If you have such an erection, which lasts continuously for more than 4 hours you should contact a doctor immediately. sudden loss of vision (frequency rare). Other side effects have been reported:
Common (seen in 1 to 10 in every 100 patients)
headache, back pain, muscle aches, pain in arms and legs, facial flushing, nasal congestion, and indigestion. Uncommon (seen in 1 to 10 in every 1,000 patients)
dizziness, stomach ache, feeling sick, being sick (vomiting), reflux, blurred vision, eye pain, difficulty in breathing, presence of blood in urine, prolonged erection, pounding heartbeat sensation, a fast heart rate, high blood pressure, low blood pressure, nose bleeds, ringing in the ears, swelling of the hands, feet or ankles and feeling tired. Rare (seen in 1 to 10 in every 10,000 patients)
fainting, seizures and passing memory loss, swelling of the eyelids, red eyes, sudden decrease or loss of hearing, hives (itchy red welts on the surface of the skin), penile bleeding, presence of blood in semen and increased sweating. Heart attack and stroke have also been reported rarely in men taking CIALIS. Most of these men had known heart problems before taking this medicine.
Partial, temporary, or permanent decrease or loss of vision in one or both eyes has been rarely reported.
Treatment is usually short lived as the use of the medicine has not been affected by medical action.
1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).
2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.
3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.
Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:
Cialis (tadalafil) can interact with certain foods and beverages, possibly altering its effectiveness or increasing the risk of side effects.
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References1. News World. February 2023. Retrieved May 13, 2022 fromhttps://news.w.org/news/news-daily-news/2023/22-2023/u-s-news-world/ Retrieved May 13, 2022 from
2.. The United States Public Service,Washington, DC:Pfizer, Inc., 2012, p. 3.Pfizer, Inc., 2015, p. 4..
January 21, 2013.https://news.w.org/news/news-daily-news/u-s-news-world/ Retrieved May 13, 2022 from
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1.. Washington, DC: American Board on Options and Assistance, 2009, p.
United States Public Service,Pfizer, Inc., 2009, p.
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Understanding Sildenafil Citrate (Viagra) is crucial in managing erectile dysfunction (ED) in men. This medication is known for its high blood pressure and improved sexual performance. This article aims to provide an in-depth look at how this medication works, its benefits, and potential risks.
Sildenafil Citrate is the active ingredient in Viagra. It is the same active ingredient found in erectile dysfunction medications like Cialis, Levitra, and Stendra. It works by increasing blood flow to the penis, helping men achieve and maintain an erection.
Sildenafil works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which is responsible for breaking down cyclic guanosine monophosphate (cGMP). cGMP is important in the erection process, particularly during sexual arousal.
Sildenafil is primarily metabolized in the liver and then distributed throughout the body. It can inhibit PDE5 enzymes, including PDE5A and PDE5C, which are responsible for breaking down cGMP. This inhibition enhances blood flow to the penis, leading to an erection.
Like all medications, Sildenafil Citrate can cause side effects, although they are generally mild and temporary. Common side effects include headaches, flushing, nasal congestion, and dizziness. More serious side effects may include vision changes, hearing loss, and prolonged erections. If any of these side effects persist or worsen, consult your healthcare provider.
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